The majority of children in a landmark study on puberty blockers experienced positive or negative changes in their mental health, new analysis suggests.

The original study of 44 children, who all took the controversial drugs for a year or more, found no mental health impact – neither benefits nor harm.

But a re-analysis of that data now suggests 34% saw their mental health deteriorate, while 29% improved.

The new study has not been in a peer-reviewed journal yet.

The authors say they felt there was an urgency in getting the information into the public domain.

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