Moderna and Merck announce “positive topline results” for a personalized mRNA cancer vaccine against melanoma — sending Moderna’s stock up 160% — and Kim cuts through the hype: the Phase 3 trial doesn’t finish until 2030, no actual data was released, the treatment requires 18–27 injections per patient, carries up to a 36% severe side-effect rate, the first person outside clinical trials to take it died, and Merck takes half the profits. The honest picture from Phase 2b: about 69 in 100 patients were still recurrence-free at five years versus 49 in 100 on Keytruda alone — genuinely promising for post-surgery melanoma, but nowhere near a “cure for cancer.” Elon Musk calls mRNA “the most promising platform in medicine”; Kim plays his old tweets charting his journey from “the science is unequivocal” to myocarditis to unlimited ketamine tolerance.
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